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黄以超
Hefei | Anhui Medical University | Professor
  邮箱   yichao.huang@ahmu.edu.cn 
TA的实验室:   环境暴露与健康实验室
论文

A review of environmental metabolism disrupting chemicals and effect biomarkers associating disease risks: Where exposomics meets metabolomics

期刊: Environment International  2022
作者: Yichao Huang,Mingliang Fang,Daniel Cozzolino,Xiaochen Huang,Jing Yang,De-Xiang Xu,Hua Wang,Runcheng Fang,Jiachen Sun
DOI:10.1016/j.envint.2021.106941

Identification of suitable technologies for drinking water quality prediction: a comparative study of traditional, ensemble, cost-sensitive, outlier detection learning models and sampling algorithms

期刊: ACS ES&T Water  2021
作者: Yongfeng Deng,Da Chen,Ruqin Shen,Yichao Huang,Min Zuo,Tianchi Lin,Luoyuan Zhang,Xiuying Xu,Houtao Liu,Xingguo Chen
DOI:10.1021/acsestwater.1c00037

Plasma lipidomics in early pregnancy and risk of gestational diabetes mellitus: a prospective nested case-control study in Chinese women.

期刊: Am J Clin Nutr  2021
作者: And An Pan*.,Da Chan*,Xiong-Fei Pan,Gang Liu,Jason Hy Wu,Chuanzhu Lv,Chun-Xia Yang,Xiaorong Qi,Shijiao Yan,Xingyue Song,Huayan Zeng,Yan Liu,Jiaying Yuan,Qi Lu,Xue Yang,Fengjiang Sun,Yi Ye,Ping Wu,Yichao Huang,Yi Wang

Biochar nanoparticles induced distinct biological effects on freshwater algae via oxidative stress, membrane damage, and nutrient depletion.

期刊: ACS Sustainable Chemistry & Engineering.  2021
作者: Da Chen,Yan Wang,Xiaodong Wang,Yichao Huang,Hongli Zhang,Shishu Zhu,Xiaochen Huang

Di (2-ethyl-hexyl) Phthalate Disrupts Placental Growth in a Dual Blocking Mode

期刊: Journal of Hazardous Materials  2021
作者: Ling-Li Zhao*.,Tao Xu,Shi-Chen Zhang,De-Xiang Xu,Lan Gao,Hua Wang,Jun Zhang,Yichao Huang,Qu-Nan Wang,Mei-Fang Sun,Yan-Ling Li,Shan-Yu Zhang,Ling-Luo Chu,Shuai Zhao,Cong-Cong Sun #
DOI:10.1016/j.jhazmat.2021.126815.

Quantitative fatty acid signature analysis (QFASA) in indoor dust: Implication for tracking indoor source accumulation of organic pollutant exposure

期刊: Environment International  2021
作者: Yichao Huang,Yunjiang Yu*,Liu Yang,Fengjiang Sun,Hongli Tan,Da Chen,Lin Tao,Jinxin Xie
DOI:10.1016/j.envint.2021.106848

A prospective study of early-pregnancy thyroid markers, lipid species, and risk of gestational diabetes mellitus

Abstract Context While the associations between thyroid markers and gestational diabetes mellitus (GDM) have been extensively studied, the results are inconclusive and the mechanisms remain unclear. Objective We aimed to investigate the prospective associations of thyroid markers in early gestation with GDM risk, and examine the mediating effects through lipid species. Methods This study included 6068 pregnant women from the Tongji-Shuangliu Birth Cohort. Maternal serum thyroid markers (free triiodothyronine (fT3), free thyroxine (fT4), thyroid-stimulating hormone, thyroid peroxidase antibody, and thyroglobulin antibody) were measured before 15 weeks. Deiodinase activity was assessed by fT3/fT4 ratio. Plasma lipidome were quantified in a subset of 883 participants. Results Mean age of the participants was 26.6 ± 3.7 years, and mean gestational age was 10.3 ± 2.0 weeks. Higher levels of fT4 were associated with a decreased risk of GDM (OR=0.73 comparing the extreme quartiles; 95% CI 0.54, 0.98, Ptrend =0.043), while higher fT3/fT4 ratio was associated with an increased risk of GDM (OR=1.43 comparing the extreme quartiles; 95% CI 1.06, 1.93, Ptrend =0.010) after adjusting for potential confounders. Multiple linear regression suggested that fT3/fT4 ratio was positively associated with alkylphosphatidylcholine 36:1, phosphatidylethanolamine plasmalogen 38:6, diacylglyceride 18:0/18:1, sphingomyelin 34:1, and phosphatidylcholine 40:7 (false discovery rate adjusted P

期刊: The Journal of Clinical Endocrinology & Metabolism  2021
作者: An Pan,Xiong-Fei Pan,Liangzhong Li*,Da Chen,Gang Liu,Yixin Wang,Chun-Xia Yang,Xiaorong Qi,Ying Wen,Huayan Zeng,Yan Liu,Jiaying Yuan,Xue Yang,Yi Ye,Yichao Huang,Ping Wu,Fengjiang Sun,Yi Wang
DOI:10.1210/clinem/dgab637

Cellular Response of Freshwater Algae to Halloysite Nanotubes: Alteration of Oxidative Stress and Membrane Function

期刊: Environmental Science: Nano.  2021
作者: Da Chen,Jing Li,Mingxian Liu,Dali Wang,Yichao Huang,Xiaochen Huang
DOI:10.1039/D1EN00531F

Gestational exposure to environmental cadmium induces placental apoptosis and fetal growth restriction via Parkin-modulated MCL-1 degradation

期刊: Journal of Hazardous Materials  2021
作者: Hua Wang,De-Xiang Xu,Yichao Huang,Xiao-Feng Xu,Ling-Li Zhao*.,Cheng Zhang,Lan Gao,Shuang Zhang,Guo-Xiang Zhou,Yi-Ting Fu,Wei-Bo Liu,Xue-Ting Shi,Yong-Wei Xiong,Li-Min Dai,Hua-Long Zhu
DOI:10.1016/j.jhazmat.2021.127268

Circulating fatty acids and risk of gestational diabetes mellitus: prospective analyses in China

Objective We aimed to examine prospective associations between circulating fatty acids in early pregnancy and incident gestational diabetes mellitus (GDM) among Chinese pregnant women. Methods Analyses were based on two prospective nested case-control studies conducted in western China (336 GDM cases and 672 matched controls) and central China (305 cases and 305 matched controls). Fasting plasma fatty acids in early pregnancy (gestational age at enrollment: 10.4 weeks [standard deviation, 2.0]) and 13.2 weeks [1.0], respectively) were determined by gas chromatography-mass spectrometry, and GDM was diagnosed based on the International Association of Diabetes in Pregnancy Study Groups criteria during 24-28 weeks of gestation. Multiple metabolic biomarkers (HOMA-IR [homeostatic model assessment for insulin resistance], HbA1c, c-peptide, high-sensitivity C-reactive protein, adiponectin, leptin, and blood lipids) were additionally measured among 672 non-GDM controls at enrollment. Results Higher levels of saturated fatty acids (SFAs) 14:0 (pooled odds ratio, 1.41 for each 1-standard deviation increase; 95% confidence interval, 1.25, 1.59) and 16:0 (1.19; 1.05, 1.35) were associated with higher odds of GDM. Higher levels of n-6 polyunsaturated fatty acid (PUFA) 18:2n-6 was strongly associated with lower odds of GDM (0.69; 0.60, 0.80). In non-GDM pregnant women, higher SFAs 14:0 and 16:0 but lower n-6 PUFA 18:2n-6 were generally correlated with unfavorable metabolic profiles. Conclusions We documented adverse associations of 14:0 and 16:0 but a protective association of 18:2n-6 with GDM among Chinese pregnant women. Our findings highlight the distinct roles of specific fatty acids in the onset of GDM.

期刊: European Journal of Endocrinology  2021
作者: Jason Hy Wu,An Pan,Zhixiong Mei,Yuanyuan Li,Da Chen,Danxia Yu,Shunqing Xu,Robert A. Gibson,Ge Liu,Chun-Xia Yang,Xue Yang,Xiaorong Qi,Huayan Zeng,Yan Liu,Ying Wen,Matti Marklund,Huan Chen,Yi Ye,Yi Wang,Xinping Li,Yichao Huang,Xiong-Fei Pan
DOI:10.1530/eje-21-0118

Enhanced reproductive toxicities induced by phthalates contaminated microplastics in male mice (Mus musculus)

期刊: Journal of Hazardous Materials  2021
作者: Yan Zhang,Hongqiang Ren,Yichao Huang,Ruqin Shen,Zehua Yan,Yongfeng Deng
DOI:10.1016/j.jhazmat.2020.124644

Postnatal exposure to DINP was associated with greater alterations of lipidomic markers for hepatic steatosis than DEHP in postweaning mice

期刊: Science of The Total Environment  2021
作者: Yichao Huang,Xiaochen Huang,Jiachen Sun,Jinxin Xie,Long Zhang,Liu Yang,Hongli Tan,Haojia Chen,Fengjiang Sun,Yan Yang
DOI:10.1016/j.scitotenv.2020.143631

Gut Microbial Metabolite p-Cresol Alters Biotransformation of Bisphenol A: Enzyme Competition or Gene Induction?

期刊: Journal of Hazardous Materials  2021
作者: Mingliang Fang,Yichao Huang,Da Chen,Yanxia Yu,Tharushi P Keerthisinghe,Haoduo Zhao,Bo Peng
DOI:10.1016/j.jhazmat.2021.128093

The effect of maturity and tissue on the ability of mid infrared spectroscopy to predict the geographical origin of banana ( Musa Cavendish )

期刊: International Journal of Food Science & Technology  2021
作者: Daniel Cozzolino,Mingliang Fang,Yongfeng Deng,Yasmina Sultanbawa,Heather E. Smyth,Michael Netzel,Da Chen,Fengjiang Sun,Yichao Huang,Long Zhang
DOI:10.1111/ijfs.14960

Lipidomic biomarkers: Potential mediators of associations between urinary bisphenol A exposure and colorectal cancer

期刊: Journal of Hazardous Materials  2021
作者: Tong Shen,Yichao Huang,Xiaoming Shi,Song Tang,Sheng Wang,Pengpeng Jiang,Xiaohui Hua,Xindong Zhang,Ming Wu,Xingcun Liu,Gengfu Wang,Xu Hong
DOI:10.1016/j.jhazmat.2021.127863

Association between pyrethroid exposure and cardiovascular disease: A national population-based cross-sectional study in the US

期刊: Environment International  2021
作者: Xiong-Fei Pan,Jay Pan,Jie Yang,Jason Hy Wu,Chun-Xia Yang,Da Chen,Yichao Huang,Ying Wen,An Pan,Qingping Xue
DOI:10.1016/j.envint.2021.106545

Novel Synthetic Antioxidants in House Dust from Multiple Locations in the Asia-Pacific Region and the United States

期刊: Environmental Science & Technology  2021
作者: And Da Chen*,Lin Tao,Yichao Huang,Liu Yang,Hongli Tan
DOI:10.1021/acs.est.1c00195.s001

Rice ACID PHOSPHATASE 1 regulates Pi stress adaptation by maintaining intracellular Pi homeostasis

期刊: Plant, Cell & Environment  2021
作者: Chuang Wang,Sheliang Wang,Yichao Huang,Fangsen Xu,Gaobing Wu,Hongmei Cai,Jian Yang,Zixuan Wu,Zezhen Du,Jingyi Li,Suren Deng
DOI:10.1111/pce.14191

Photodegradation of 1,3,5-Tris-(2,3-dibromopropyl)-1,3,5-triazine-2,4,6-trione and decabromodiphenyl ethane flame retardants: Kinetics, Main products, and environmental implications

期刊: Journal of Hazardous Materials  2020
作者: Da Chen,Yan Wang,Hongli Tan,Weijie Su,Yichao Huang,Xiaotu Liu,Xiaoshi Zheng,Daming Zhou
DOI:10.1016/j.jhazmat.2020.122983

Exposure to bisphenol analogues interrupts growth, proliferation, and fatty acid compositions of protozoa Tetrahymena thermophila

期刊: Journal of Hazardous Materials  2020
作者: Da Chen,Zhiqiang Sun,Hexia Chen,Yichao Huang,Sen Hou,Jie Wang,Jing Li
DOI:10.1016/j.jhazmat.2020.122643

Rapid measurement of microplastic contamination in chicken meat by mid infrared spectroscopy and chemometrics: A feasibility study

期刊: Food Control  2020
作者: Daniel Cozzolino,Yongfeng Deng,James Chapman,Yichao Huang
DOI:10.1016/j.foodcont.2020.107187

Nutritional and Environmental Contaminant Exposure: A Tale of Two Co-Existing Factors for Disease Risks

期刊: Environmental Science & Technology  2020
作者: Mingliang Fang,Yichao Huang
DOI:10.1021/acs.est.0c05658

Lipidomic Changes in Banana (Musa cavendish) during Ripening and Comparison of Extraction by Folch and Bligh–Dyer Methods

期刊: Journal of Agricultural and Food Chemistry  2020
作者: Daniel Cozzolino,Yichao Huang,Hongli Tan,Da Chen,Hexia Chen,Fengjiang Sun
DOI:10.1021/acs.jafc.0c04236

Microplastics release phthalate esters and cause aggravated adverse effects in the mouse gut

期刊: Environment International  2020
作者: Bernardo Lemos,Yan Zhang,Hongqiang Ren,Yichao Huang,Meng Wang,Ruqin Shen,Zehua Yan,Yongfeng Deng
DOI:10.1016/j.envint.2020.105916

Measuring thiamine status in dried blood spots

期刊: Clinica Chimica Acta  2020
作者: Timothy J. Green,Robert A. Gibson,Yichao Huang
DOI:10.1016/j.cca.2020.06.011

Association of circulating saturated fatty acids with the risk of pregnancy-induced hypertension: a nested case–control study

期刊: Hypertension Research  2020
作者: Yuanyuan Li,Da Chen,Shunqing Xu,Wei Xia,Xia Huo,Aifen Zhou,Xiaomei Chen,Yi Wu,Weijie Su,Chenhui Yang,Wenxin Zhang,Yichao Huang,Xinping Li
DOI:10.1038/s41440-019-0383-7

Comparative analysis of surface water quality prediction performance and identification of key water parameters using different machine learning models based on big data

期刊: Water Research  2020
作者: Hongqiang Ren,Yongfeng Deng,Xingguo Chen,Da Chen,Yan Zhang,Jinfeng Wang,Xinyi Zou,Min Zuo,Fengrui Liu,Ruqin Shen,Xiangyang Qi,Yichao Huang,Chuanlong Zhou,Hexia Chen,Kangyang Chen
DOI:10.1016/j.watres.2019.115454

Changes to breast milk fatty acid composition during storage, handling and processing: A systematic review

期刊: Prostaglandins, Leukotrienes and Essential Fatty Acids  2019
作者: Robert A. Gibson,Andrew J. Mcphee,Yi-Chao Huang,Philippa F. Middleton,Jacqueline Miller,Chang Gao
DOI:10.1016/j.plefa.2019.04.008

DEHP and DINP Induce Tissue- and Gender-Specific Disturbances in Fatty Acid and Lipidomic Profiles in Neonatal Mice: A Comparative Study

期刊: Environmental Science & Technology  2019
作者: Da Chen,Jing Li,Hexia Chen,Zhiqiang Sun,Yongfeng Deng,Hongli Tan,Fengjiang Sun,Yichao Huang
DOI:10.1021/acs.est.9b04369

Robust measurement of vitamin A status in plasma and blood dried on paper

期刊: Prostaglandins, Leukotrienes and Essential Fatty Acids  2015
作者: Robert Alan Gibson,Peter Roy Clements,Yichao Huang
DOI:10.1016/j.plefa.2015.10.001

Measurement of Fructose, Glucose, Maltose and Sucrose in Barley Malt Using Attenuated Total Reflectance Mid-infrared Spectroscopy

期刊: Food Analytical Methods  2015
作者: Daniel Cozzolino,John Carragher,Yichao Huang
DOI:10.1007/s12161-015-0286-4

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