简历详情
论文
Computational design of transmembrane pores
期刊: Nature 2020作者: David Baker,William A. Catterall,Tomoaki Matsuura,Ben F. Luisi,Justin M. Kollman,Frank Dimaio,Lance Stewart,Po-Ssu Huang,Scott E. Boyken,Eric M. Lynch,Dan Ma,Jiayi Dou,T. J. Brunette,Yang Hsia,Gabriella Reggiano,Hua Bai,Daohua Jiang,Qi Xu,Matthew J. Bick,Atsuko Uyeda,Matthew C. Johnson,Xue Y. Pei,Tamer M. Gamal El-Din,Peilong Lu,Chunfu Xu
DOI:10.1038/s41586-020-2646-5
When de novo-designed protein logics meet CAR-T therapies
期刊: Cell Research 2020作者: Peilong Lu,Mingqi Xie
DOI:10.1038/s41422-020-00419-z
Programmable design of orthogonal protein heterodimers
期刊: Nature 2018作者: David Baker,Vicki H. Wysocki,Nikolaos G. Sgourakis,Frank Dimaio,Lauren P. Carter,Vikram Khipple Mulligan,T. J. Brunette,Sherry Bermeo,Robert A. Langan,Aniruddha Sahasrabuddhe,Zachary L. Vanaernum,Peilong Lu,Matthew J. Bick,David Flores-Solis,Florian Busch,Mengxuan Jia,Scott E. Boyken,Zibo Chen
DOI:10.1038/s41586-018-0802-y
Accurate computational design of multipass transmembrane proteins
期刊: Science 2018作者: David Baker,James U. Bowie,Wenqing Xu,Vikram Khipple Mulligan,William Sheffler,George Ueda,Jorge A. Fallas,Zibo Chen,Scott E. Boyken,Michael D. Vahey,Kathy Y. Wei,Frank Dimaio,Duyoung Min,Peilong Lu
DOI:10.1126/science.aaq1739
Structural basis for gating pore current in periodic paralysis
期刊: Nature 2018作者: William A. Catterall,Ning Zheng,Régis Pomès,Peilong Lu,Christopher Ing,Tamer M. Gamal El-Din,Daohua Jiang
DOI:10.1038/s41586-018-0120-4
Crystal structure of a membrane-bound O-acyltransferase
期刊: Nature 2018作者: Wenqing Xu,Zihe Rao,Houra Merrikh,Xin Li,Peilong Lu,Kevin S. Lang,Christopher N. Merrikh,Zhizhi Wang,Dan Ma
DOI:10.1038/s41586-018-0568-2
An atomic structure of human γ-secretase
期刊: Nature 2015作者: Yigong Shi,Sjors H. W. Scheres,Rui Zhou,Linfeng Sun,Dan Ma,Peilong Lu,Guanghui Yang,Chuangye Yan,Xiao-Chen Bai
DOI:10.1038/nature14892
Structure and mechanism of a eukaryotic transmembrane ascorbate-dependent oxidoreductase
期刊: Proceedings of the National Academy of Sciences 2014作者: Yigong Shi,Mingjian Du,Xinqi Gong,Chuangye Yan,Dan Ma,Peilong Lu
DOI:10.1073/pnas.1323931111
Crystal structure of the γ-secretase component nicastrin
期刊: Proceedings of the National Academy of Sciences 2014作者: Yigong Shi,Dan Ma,Peilong Lu,Guanghui Yang,Linfeng Sun,Yanyu Zhao,Rui Zhou,Chuangye Yan,Tian Xie
DOI:10.1073/pnas.1414837111
Three-dimensional structure of human γ-secretase
期刊: Nature 2014作者: Yigong Shi,Sjors H. W. Scheres,Rui Zhou,Yanyu Zhao,Guanghui Yang,Linfeng Sun,Chuangye Yan,Tian Xie,Dan Ma,Xiao-Chen Bai,Peilong Lu
DOI:10.1038/nature13567
Substrate Selectivity of the Acid-activated Glutamate/γ-Aminobutyric acid (GABA) Antiporter GadC fromEscherichia coli
期刊: Journal of Biological Chemistry 2013作者: Yigong Shi,Peilong Lu,Dan Ma
DOI:10.1074/jbc.m113.474502
L-glutamine provides acid resistance for Escherichia coli through enzymatic release of ammonia
期刊: Cell Research 2013作者: Yigong Shi,Haiteng Deng,Guo-Qiang Chen,Yingying Guo,Yuling Chen,Dan Ma,Peilong Lu
DOI:10.1038/cr.2013.13
Structure and mechanism of a glutamate–GABA antiporter
期刊: Nature 2012作者: Yigong Shi,Jiawei Wang,Ping Yin,Chao Fan,Chuangye Yan,Peilong Lu,Dan Ma
DOI:10.1038/nature10917
Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein
期刊: Cell Research 2012作者: Yigong Shi,Li Yu,Ning Gao,Lei Liu,Haiteng Deng,Feng-Liang Wang,Peilong Lu,Yuan Tian,Mei Liu,Meisheng Ma,Qiang Guo,Na Mi,Wanqiu Hu,Wooyoung Choi,Weijiao Huang
DOI:10.1038/cr.2012.24
Structure of the mRNA splicing complex component Cwc2: insights into RNA recognition
期刊: Biochemical Journal 2012作者: Ping Yin,Wenqi Li,Li Wang,Chuangye Yan,Guifeng Lu,Peilong Lu
DOI:10.1042/bj20111385
Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel
期刊: Nature 2009作者: Yigong Shi,Nieng Yan,Pengye Wang,Ya-Nan Xu,Peilong Lu,Weijiao Huang,Chao Cheng,Jiawei Wang,Yongjian Huang,Yi Wang
DOI:10.1038/nature08610