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张坤
  邮箱   zhang1986kun@126.com 
TA的实验室:   生物靶向诊疗超声实验室
论文

Ultrasound-Based Drug Delivery System

期刊: Current Medicinal Chemistry  2021
作者: Kun Zhang,Li-Ping Sun,Shi-Hao Xu,Wei-Wei Ren

Switching Reactive Oxygen Species into Reactive Nitrogen Species by Photo-Cleaved O2-Released Nanoplatforms Favors Hypoxic Tumor Repression

期刊: Advanced Science  2021
作者: Kun Zhang,Junjie Liu,Danke Su,Hongxue Li,Guanhua Qiu,Jingchen Liang,Yan Liu,Ying Xie,Chuangye Han,Yan Zhang,Lidong Liu,Duo Wang,Tao Luo
DOI:10.1002/advs.202101065

Fluorocarbon-driven photosensitizer assembly decodes energy conversion pathway for suppressing breast tumor

期刊: Nano Today  2021
作者: Bin He,Jun Cao,Kun Zhang,Rongrong Chu,Wenxiong Shi,Zhaoyuan Guo,Yan Zhang,Xuequan Zhang,Shengsheng Cai,Xiaoxian Zhang,Heng Mei

Nanotechnology-Enabled Chemodynamic & Immunotherapy

期刊: Current Cancer Drug Target  2021
作者: Kun Zhang,Xiaohong Xu,Taixia Wang

Continuous Inertial Cavitation Evokes Massive ROS for Reinforcing Sonodynamic Therapy and Immunogenic Cell Death against Breast Carcinoma

期刊: Nano Today  2021
作者: Kun Zhang,Huixiong Xu,Yu Chen,Chongke Zhao,Xiaolong Li,Guang Xu,Yan Zhang,Chunxia Su,Hongyan Li,Liping Sun,Xingwu Jiang#,Yifei Yin#

Reactive Oxygen Species Scavenging and Inflammation Mitigation Enabled by Biomimetic Prussian Blue Analogues Boycott Atherosclerosis

期刊: Journal of Nanobiotechnology  2021
作者: Huixiong Xu,Kun Zhang,Chunxia Su,Liping Sun,Haohao Yin,Taixia Wang,Hongyan Li,Wei Zhang,Yifei Yin#,Yan Zhang

Nanobiotechnology-Enabled Energy Utilization Elevation for Augmenting Minimally-Invasive & Noninvasive Oncology Thermal Ablation

期刊: Wiley Interdisciplinary Reviews——Nanomedicine & Nanobiotechnology  2021
作者: Kun Zhang,Chao Fang,Hongyan Li,Lixia Duan,Fanlei Li,Lehang Guo,Yan Zhang

Thermal Ablation of Benign Thyroid Nodules and Papillary Thyroid Microcarcinoma

期刊: Frontiers in Oncology  2020
作者: Kun Zhang,Li-Ping Sun,Hui-Xiong Xu,Feng Lu,Xiao-Wan Bo
DOI:10.3389/fonc.2020.580431

Tumor Metabolism-Engineered Composite Nanoplatforms Potentiate Sonodynamic Therapy via Reshaping Tumor Microenvironment and Facilitating Electron-Hole Pairs’ Separation

期刊: Advanced Functional Materials  2020
作者: Kun Zhang,Hui-Xiong Xu,Li-Ping Sun,Chang Liu,Wen-Wen Yue,Bang-Guo Zhou,Yan Zhang,Guang Xu,Xiao-Hong Xu,Hao-Hao Yin,Xin Guan
DOI:10.1002/adfm.202000326

Correlation between Ultrasound Consolidated Score and Simple Endoscopic Score for Determining the Activity of Crohn’s Disease

期刊: The British Journal of Radiology  2020
作者: Hui-Xiong Xu,Xiao‐Rong Xu,Qiao Wang,Xiao-Long Li,Chong-Ke Zhao,Wei-Wei Ren,Xiao‐Min Sun,Yi-Feng Zhang,Li-Ping Sun,Le-Hang Guo,Lin-Na Liu,Kun Zhang,Shi-Si Ding,Chang Liu
DOI:10.1259/bjr.20190614

Extravascular gelation shrinkage-derived internal stress enables tumor starvation therapy with suppressed metastasis and recurrence

期刊: Nature Communications  2019
作者: Huixiong Xu,Yu Chen,Liping Sun,Chang Liu,Hongyan Li,Dou Du,Weiwei Ren,Wenwen Yue,Bangguo Zhou,Yinying Pu,Xin Guan,Haohao Yin,Yaping He,Yan Fang,Kun Zhang
DOI:10.1038/s41467-019-13115-3

Checkpoint blockade and nanosonosensitizer-augmented noninvasive sonodynamic therapy combination reduces tumour growth and metastases in mice

期刊: Nature Communications  2019
作者: Yu Chen,Huixiong Xu,Kun Zhang,Liping Sun,Yifeng Zhang,Lehang Guo,Chang Liu,Weiwei Ren,Haohao Yin,Bangguo Zhou,Luodan Yu,Liang Chen,Wenwen Yue
DOI:10.1038/s41467-019-09760-3

Radiofrequency-Sensitive Longitudinal Relaxation Tuning Strategy Enabling the Visualization of Radiofrequency Ablation Intensified by Magnetic Composite

期刊: ACS Applied Materials & Interfaces  2019
作者: Kun Zhang,Xin Guan,Rong Wu,Li-Hua Xiang,Wei-Zhong Tang,Shi-Si Ding,Wei-Wei Ren,Shi-Hao Xu,Hao-Hao Yin,Hong-Yan Li,Yan Fang
DOI:10.1021/acsami.9b02401

Intensified Stiffness and Photodynamic Provocation in a Collagen‐Based Composite Hydrogel Drive Chondrogenesis

期刊: Advanced Science  2019
作者: Jinmin Zhao,Kun Zhang,Zhenhui Lu,Zainen Qin,Xiaojing Cheng,Sijia Liu,Li Zheng
DOI:10.1002/advs.201900099

Quantum Yield‐Engineered Biocompatible Probes Illuminate Lung Tumor Based on Viscosity Confinement‐Mediated Antiaggregation

期刊: Advanced Functional Materials  2019
作者: Chuan Xu,Yong‐Xiang Zhao,Hong Wu,Yan Fang,Dou Du,Yi‐Fei Yin,Wen-Wen Yue,Xiao‐Tong Li,Jin‐Yi Lang,Hong-Yan Li,Kun Zhang
DOI:10.1002/adfm.201905124

Usefulness of Strain Elastography, ARFI Imaging, and Point Shear Wave Elastography for the Assessment of Crohn Disease Strictures

期刊: Journal of Ultrasound in Medicine  2019
作者: Rong Wu,Chang Liu,Xiao‐Min Sun,Xiao‐Rong Xu,Kun Zhang,Guang Xu,Huan Pu,Hui Liu,Li-Hua Xiang,Chong-Ke Zhao,Jing Wan,Yan Fang,Shi-Si Ding
DOI:10.1002/jum.14989

Coordination-Responsive Longitudinal Relaxation Tuning as a Versatile MRI Sensing Protocol for Malignancy Targets

期刊: Advanced Science  2018
作者: Yongxiang Zhao,Huixiong Xu,Lehang Guo,Dan Wang,Chang Liu,Liping Sun,Weiwei Ren,Yu Cheng,Kun Zhang
DOI:10.1002/advs.201800021

Three-Dimensional Shear Wave Elastography for Differentiating Benign From Malignant Thyroid Nodules

期刊: Journal of Ultrasound in Medicine  2018
作者: Hui-Xiong Xu,Qing Wei,Shen Qu,Kun Zhang,Wen-Wen Yue,Dan Wang,Qiao Wang,Ya-Ping He,Azra Alizad,Shi-Gao Chen,Chong-Ke Zhao
DOI:10.1002/jum.14531

Nanosized Hollow Colloidal Organosilica Nanospheres with High Elasticity for Contrast-Enhanced Ultrasonography of Tumors

期刊: ACS Biomaterials Science & Engineering  2017
作者: Hang-Rong Chen,Yong-Hua Xua,Kun Zhang,Yi Wang
DOI:10.1021/acsbiomaterials.7b00779

Oxygen-Self-Produced Nanoplatform for Relieving Hypoxia and Breaking Resistance to Sonodynamic Treatment of Pancreatic Cancer

期刊: ACS Nano  2017
作者: Junjie Liu,Yongxiang Zhao,Kun Zhang,Tao Luo,Hongxue Li,Wei Zhang,Yan Liu,Honglin Luo,Jie Chen
DOI:10.1021/acsnano.7b08225

Phase-transitional Fe3O4/perfluorohexane Microspheres for Magnetic Droplet Vaporization

期刊: Theranostics  2017
作者: Yuanyi Zheng,Tao Ying,Bing Hu,Zhigang Wang,Pan Li,Kun Zhang,Xiaojun Cai,Hangrong Chen,Jinshun Xu,Wei Gao,Yu Chen,Ping Zhang,Yang Zhou,Ronghui Wang
DOI:10.7150/thno.17251

Comparison of fine needle aspiration and non-aspiration cytology for diagnosis of thyroid nodules: A prospective, randomized, and controlled trial

期刊: Clinical Hemorheology and Microcirculation  2017
作者: Qing Wei,Kun Zhang,Feng Lu,Li-Ping Sun,Chong-Ke Zhao,Xiao-Wan Bo,Ya-Ping He,Xiao-Long Li,Le-Hang Guo,Hui-Xiong Xu,Hui-Jun Fu,Dan Wang
DOI:10.3233/ch-160222

Ultrasound-Triggered Nitric Oxide Release Platform Based on Energy Transformation for Targeted Inhibition of Pancreatic Tumor

期刊: ACS Nano  2016
作者: Hangrong Chen,Liping Sun,Ming Ma,Yu Chen,Xiaoqing Jia,Huixiong Xu,Kun Zhang
DOI:10.1021/acsnano.6b04921

Continuous Cavitation Designed for Enhancing Radiofrequency Ablation via a Special Radiofrequency Solidoid Vaporization Process

期刊: ACS Nano  2016
作者: Huixiong Xu,Xiaolong Li,Xiaowan Bo,Hangrong Chen,Pei Li,Kun Zhang
DOI:10.1021/acsnano.5b07486

Synergistic retention strategy of RGD active targeting and radiofrequency-enhanced permeability for intensified RF & chemotherapy synergistic tumor treatment

期刊: Biomaterials  2016
作者: Huixiong Xu,Hangrong Chen,Dandan Li,Xiaolong Li,Xiaowan Bo,Yaping He,Pei Li,Kun Zhang
DOI:10.1016/j.biomaterials.2016.05.014

Combination of two-dimensional shear wave elastography with ultrasound breast imaging reporting and data system in the diagnosis of breast lesions: a new method to increase the diagnostic performance

期刊: European Radiology  2015
作者: Kun Zhang,Yi-Feng Zhang,Jun-Mei Xu,Rong Wu,Xiao-Long Li,Xiao-Wan Bo,Le-Hang Guo,Hui-Xiong Xu,Dan-Dan Li
DOI:10.1007/s00330-015-4163-8

A Versatile Nanotheranostic Agent for Efficient Dual-Mode Imaging Guided Synergistic Chemo-Thermal Tumor Therapy

期刊: Advanced Functional Materials  2015
作者: Hangrong Chen,Jianlin Shi,Yuanyi Zheng,Shige Wang,Ming Ma,Kun Zhang,Wei Gao,Xiaoqing Jia,Xiaojun Cai
DOI:10.1002/adfm.201403991

Ultrasmall Cu2-xS Nanodots for Highly Efficient Photoacoustic Imaging-Guided Photothermal Therapy

期刊: Small  2015
作者: Hangrong Chen,Jianlin Shi,Yu Chen,Kun Zhang,Jin Wang,Liang Song,Huixiong Xu,Chengbo Liu,Pei Li,Juan Mou
DOI:10.1002/smll.201403249

Perfluoropentane-Encapsulated Hollow Mesoporous Prussian Blue Nanocubes for Activated Ultrasound Imaging and Photothermal Therapy of Cancer

期刊: ACS Applied Materials & Interfaces  2015
作者: Hangrong Chen,Jianlin Shi,Huixia Wu,Ming Ma,Kun Zhang,Huixiong Xu,Shige Wang,Yu Chen,Xiaojun Cai,Xiaoqing Jia
DOI:10.1021/am507443p

CO2 bubbling-based 'Nanobomb' System for Targetedly Suppressing Panc-1 Pancreatic Tumor via Low Intensity Ultrasound-activated Inertial Cavitation

期刊: Theranostics  2015
作者: Jianlin Shi,Yuanyi Zheng,Juan Mou,Ronghui Wang,Xiaojun Cai,Shuguang Zheng,Xiaoqing Jia,Hangrong Chen,Huixiong Xu,Kun Zhang
DOI:10.7150/thno.12691

Marriage Strategy of Structure and Composition Designs for Intensifying Ultrasound & MR & CT Trimodal Contrast Imaging

期刊: ACS Applied Materials & Interfaces  2015
作者: Huixiong Xu,Zeng Zeng,Xiaolong Li,Xiaowan Bo,Pei Li,Hangrong Chen,Kun Zhang
DOI:10.1021/acsami.5b04999

Facile synthesis of liposome/Cu2−x S-based nanocomposite for multimodal imaging and photothermal therapy

期刊: Science China Materials  2015
作者: Jianlin Shi,Hangrong Chen,Chenyang Wei,Kun Zhang,Ming Ma,Yu Chen,Juan Mou
DOI:10.1007/s40843-015-0044-3

Double-scattering/reflection in a Single Nanoparticle for Intensified Ultrasound Imaging

期刊: Scientific Reports  2015
作者: Jianlin Shi,Hairong Zheng,Yuanyi Zheng,Dong Zhang,Xiasheng Guo,Hangrong Chen,Kun Zhang
DOI:10.1038/srep08766

A Drug-Perfluorocarbon Nanoemulsion with an Ultrathin Silica Coating for the Synergistic Effect of Chemotherapy and Ablation by High-Intensity Focused Ultrasound

期刊: Advanced Materials  2014
作者: Jianlin Shi,Faqi Li,Xiaojun Cai,Minghua Yao,Rong Wu,Shuguang Zheng,Qi Wang,Kun Zhang,Xiaoqing Jia,Hangrong Chen,Huixiong Xu,Ming Ma
DOI:10.1002/adma.201402969

Unconventional Pd nanoparticles' growth induced by a competitive effect between temperature-dependent coordination and reduction of grafted amino ligands for Heck reaction

期刊: J. Mater. Chem. A  2014
作者: Jianlin Shi,Yu Chen,Xia Wang,Guobin Zhang,Yun Gong,Xiaoxia Zhou,Hangrong Chen,Kun Zhang
DOI:10.1039/c3ta14171c

A combined “RAFT” and “Graft From” polymerization strategy for surface modification of mesoporous silica nanoparticles: towards enhanced tumor accumulation and cancer therapy efficacy

A novel modification route integrating the copolymers of positive charged quaternary amines and polyethylene glycol units using a combination “Raft” and “Graft From” strategy.

期刊: J. Mater. Chem. B  2014
作者: Jianlin Shi,Rong Wu,Huixiong Xu,Juan Mou,Xiaoqing Jia,Kun Zhang,Minghua Yao,Hangrong Chen,Shuguang Zheng,Ming Ma
DOI:10.1039/c3tb21666g

A continuous tri-phase transition effect for HIFU-mediated intravenous drug delivery

期刊: Biomaterials  2014
作者: Jianlin Shi,Xia Wang,Juan Mou,Yu Chen,Xiaoqing Jia,Ming Ma,Huixiong Xu,Shuguang Zheng,Qi Wang,Faqi Li,Hangrong Chen,Kun Zhang
DOI:10.1016/j.biomaterials.2014.03.043

Highly efficient light-induced hydrogen evolution from a stable Pt/CdS NPs-co-loaded hierarchically porous zeolite beta

期刊: Applied Catalysis B: Environmental  2014
作者: Jianlin Shi,Guiju Tao,Yu Chen,Yan Zhu,Xiangqian Fan,Kun Zhang,Yuanyuan Sun,Hangrong Chen,Xiaoxia Zhou
DOI:10.1016/j.apcatb.2014.01.024

A Gd-doped Mg-Al-LDH/Au nanocomposite for CT/MR bimodal imagings and simultaneous drug delivery

期刊: Biomaterials  2013
作者: Jianlin Shi,Yanqing Hua,Weijun Peng,Liangping Zhou,Xiangpeng Zheng,Wenbo Bu,Kun Zhang,Limin Pan,Qingguo Ren,Shengjian Zhang,Huaiyong Xing,Lijun Wang
DOI:10.1016/j.biomaterials.2013.01.070

Au-nanoparticle coated mesoporous silica nanocapsule-based multifunctional platform for ultrasound mediated imaging, cytoclasis and tumor ablation

期刊: Biomaterials  2013
作者: Jianlin Shi,Deping Zeng,Kun Zhang,Yu Chen,Ming Ma,Yuanyi Zheng,Hangrong Chen,Xia Wang
DOI:10.1016/j.biomaterials.2012.11.044

An Intelligent Nanotheranostic Agent for Targeting, Redox-Responsive Ultrasound Imaging, and Imaging-Guided High-Intensity Focused Ultrasound Synergistic Therapy

期刊: Small  2013
作者: Jianlin Shi,Huixiong Xu,Lixin Jiang,Yu Chen,Shuguang Zheng,Deping Zeng,Faqi Li,Ming Ma,Kun Zhang,Hangrong Chen,Xia Wang
DOI:10.1002/smll.201302846

Manganese oxide-based multifunctionalized mesoporous silica nanoparticles for pH-responsive MRI, ultrasonography and circumvention of MDR in cancer cells

期刊: Biomaterials  2012
作者: Jianlin Shi,Linlin Zhang,Kun Zhang,Xia Wang,Yaping Li,Zheng Wang,Haiyun Qu,Yang Sun,Yuanyi Zheng,Hangrong Chen,Shengjian Zhang,Xiufeng Ji,Qi Yin,Yu Chen
DOI:10.1016/j.biomaterials.2012.06.059

Hyaluronic acid-conjugated mesoporous silica nanoparticles: excellent colloidal dispersity in physiological fluids and targeting efficacy

期刊: Journal of Materials Chemistry  2012
作者: Jianlin Shi,Xiangzhi Cui,Xia Wang,Kun Zhang,Yu Chen,Hangrong Chen,Ming Ma
DOI:10.1039/c2jm15489g

Perfluorohexane-Encapsulated Mesoporous Silica Nanocapsules as Enhancement Agents for Highly Efficient High Intensity Focused Ultrasound (HIFU)

期刊: Advanced Materials  2012
作者: Jianlin Shi,Qi Wang,Deping Zeng,Yuanyi Zheng,Faqi Li,Kun Zhang,Ming Ma,Yu Chen,Hangrong Chen,Xia Wang
DOI:10.1002/adma.201104033

A facile in situ hydrophobic layer protected selective etching strategy for the synchronous synthesis/modification of hollow or rattle-type silica nanoconstructs

期刊: Journal of Materials Chemistry  2012
作者: Jianlin Shi,Deping Zeng,Lijun Wang,Xia Wang,Ming Ma,Yu Chen,Yuanyi Zheng,Hangrong Chen,Kun Zhang
DOI:10.1039/c2jm31504a

Multifunctional Mesoporous Composite Nanocapsules for Highly Efficient MRI-Guided High-Intensity Focused Ultrasound Cancer Surgery

期刊: Angewandte Chemie  2011
作者: Jianlin Shi,Linlin Zhang,Qianjun He,Ming Ma,Kun Zhang,Xia Wang,Shengjian Zhang,Faqi Li,Deping Zeng,Yuanyi Zheng,Yang Sun,Hangrong Chen,Yu Chen
DOI:10.1002/ange.201106180

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